Bacteriophages reduce pathogenic Escherichia coli counts in mice without distorting gut microbiota

Phage administration was effective in reducing viable E. coli in infected mice with a similar efficacy to ampicillin therapy. However, the F.O.P. bacteriophage preparation had less impact on the gut microbiota compared to ampicillin


Bacteriophage Applications for Food Production and Processing

One promising technique is bacteriophage biocontrol, a green and natural method that uses lytic bacteriophages isolated from the environment to specifically target pathogenic bacteria and eliminate them from (or significantly reduce their levels in) foods


Hierarchically structured, bioactive hydrogels with bundles of phage nanofilamentsa

Bacteriophages are essentially bionanoparticles with a protein coat, the building blocks for bottom-up synthesis of multifunctional materials with advanced properties


Perspectives on phage-antibiotic synergy in clinical applications of phage therapy

Some current studies that have addressed synergistic killing activity between phages and antibiotics, the issues of treatment order and antibiotic class, and point to considerations that will have to be addressed by future studies are discussed


Bacteriophage versus antibiotic therapy on gut bacterial communities of juvenile green turtle

The work offered the proof of concept of phage therapy to manipulate transient as well as indigenous bacterial flora in gut‐related dysbiosis of turtles


Phage therapy of pneumonia and inflammatory response

The rapid lysis of bacteria by bacteriophages in vivo does not increase the innate inflammatory response compared to antibiotic treatment


Therapeutic potential of phages in autoimmune liver diseases

Bacterial viruses (phages) have been recognized increasingly as immunomodulators contributing to immune homeostasis and curbing inflammation


Phage therapy treats patient with drug-resistant mycobacterial infection

A 15-year-old patient with cystic fibrosis with a disseminated Mycobacterium abscessus infection was treated with a three-phage cocktail following bilateral lung transplantation


Effects of Supplemental Bacteriophage Intake on Inflammation and Gut Microbiota

Effects of a cocktail of Escherichia coli-targeting bacteriophages on gut microbiota and markers of intestinal and systemic inflammation in a healthy human population were examined


The Perfect Predator

The Perfect Predator by Steffanie Strathdee and Tom Patterson – а bracing medical thriller about one woman’s race to save her husband from a lethal, antibiotic-resistant superbug


Successful treatment of antibiotic resistant bone infection with phages and antibiotics

A patient with a trauma-related left tibial infection associated with XDR Acinetobacter baumannii and MDR Klebsiella  pneumoniae  was treated with bacteriophages and antibiotics


Virus can help treat Pseudomonas aeruginosa in cystic fibrosis

A new study shows that bacteriophages can be used to fight Pseudomonas aeruginosa, the most common bacteria found in cystic fibrosis patients


Bacteriophages of the Human Gut

Scientists from University College Cork review the composition and physiological relevance of human gut bacteriophages


WHO: Keep antibiotics working – limit their use this flu season

Antibiotics need to be used with care to preserve their effectiveness for when they are truly needed


Phage Therapy: Beyond Antibacterial Action

Data obtained strongly suggest that phages may induce immunomodulatory effects which can be used in the clinic in phagotherapy


Safety and efficacy of a bacteriophage cocktail in an in vivo model of sinusitis

Pseudomonas aeruginosa  phage cocktail in a sheep model of rhinosinusitis was able to decrease sinus pathogen biofilm. No safety concerns were noted


Antimicrobial assessment of phage therapy of biofilm infection

Phage therapy constitutes a very promising approach in the control of topical microbial populations


Bacteriophages could aid disinfection of drug-resistant bacteria in wastewater

A new study shows that these pathogenic bacteria can be killed cheaply and quickly by a combined treatment with sunlight and bacteria-killing viruses called bacteriophages


Phage Studies in the USA in 2019

Two phage clinical trials will launch in the USA  in 2019. The trials will evaluate the safety, tolerability and efficacy of experimental bacteriophage therapy  in people with Crohn's disease and VADs infected by resistant S. aureus


Phage Therapy one of the Top 10 Drug Discovery Trends to Watch in 2019

Researchers from across disciplines at Charles River discuss which trends they expect will propel the development of novel therapeutics forward this year. Phage Therapy one of the Top 10 Drug Discovery Trends to Watch in 2019


Microbiome Movement - Drug Development Summit Europe 2019

The 3rd Microbiome Movement – Drug Development Europe (28-30 January 2019) returns as the industry-defining forum to help discover, develop and deliver the next generation of microbiome-based therapeutic and diagnostic candidates to market


Do infections increase the risk of subsequent mental disorders during childhood and adolescence?

A nationwide study in Denmark have shown the association between treated infections and the subsequent risk of treated mental disorders in children and adolescent


Bacteriophages Synergize with the Gut Microbiota To Combat Salmonella

Phage treatment has high specificity when combating Salmonella infection and offers a noninvasive alternative to antibiotic treatment


Cross-kingdom communication led to a breakthrough phage therapy

Princeton biologists have identified a virus, VP882, that can listen in on bacterial conversations - and then they found a way to use that to make it attack bacterial diseases like E. coli and cholera


Аntimicrobial Use and Resistance Map

ResistanceMap is an open interactive collection of charts and maps that summarize national and subnational data on antimicrobial use and resistance worldwide 


PhagoBurn Project: Important Findings

Phagoburn is a project funded by the European Union under the 7th Framework Programme for Research and Development. Phagoburn was launched on June 1st, 2013


Bacteriophage Market Expected To Exhibit Steady Growth

In the latest market report the global bacteriophage market was valued at US$ 567.9 Mn in 2017 expanding at a CAGR of 3.9% from 2018 to 2026