27.08.2021
How can “training” improve the efficiency of phages?
"Training" phages to coevolve with bacteria allows them to bypass bacterial resistance mechanisms.
15.08.2021
The 24th Evergreen Phage 2021 conference has taken place!
The 24th International Bacteriophage Conference, the oldest and most renowned gathering of scientists and enthusiasts of bacterial virus research, was held at The Evergreen College in Olympia, Washington, USA, on August 2-5, 2021.
06.08.2021
Bacteriophages against Clostridium difficile infection
Uncontrolled proliferation of C. difficile is observed predominantly in patients with significant disturbances in the intestinal microbiota due to long-term antibiotic therapy.
08.07.2021
Tens of thousands of species of phages live in the intestines of every person
After analyzing human stool samples, scientists identified 54,118 types of viruses, most of which turned out to be bacterial viruses – bacteriophages.
29.06.2021
Clinical trials of phage therapy for urinary tract infections have begun
Phase I/II clinical trials are designed to evaluate the efficacy and safety of personalized phage preparations in patients with urinary tract infections (UTIs) caused by multidrug-resistant bacteria.
10.06.2021
Mycobacteriophages: a cocktail against tuberculosis
Scientists have created a phage cocktail of five mycobacteriophages with broad specificity against M. tuberculosis strains. The properties of the bacteriophages in the cocktail were further optimized using genetic and genetic engineering approaches.
23.05.2021
WHO notes global shortage of innovative antibiotics
None of the 43 antibiotics currently in various stages of testing address the problem of multidrug resistance in dangerous pathogenic bacteria.
15.05.2021
Phage therapy for patients after spinal cord injury
Bacteriophages as a treatment for infections caused by multidrug-resistant bacteria hold great potential for patients who have suffered spinal cord injuries. Doctors from the University Hospital of Zurich discuss this in an article in the journal Spinal Cord.
24.04.2021
Bacteriophages help early detection of Lyme disease
A new PCR test has been developed for the early diagnosis of Lyme disease. The test detects a gene belonging not to the bacteria that causes the disease, but to a specific bacteriophage. If the bacteriophage is found, then the bacteria is present!
19.04.2021
Phage cocktail as the basis for a vaccine against COVID-19
The weekly online publication Capsid & Tail suggests considering bacteriophages as the basis for creating "vaccine cocktails" against COVID-19, providing long-term protection against various strains of the SARS-CoV-2 coronavirus.
10.04.2021
Phage therapy is being tested in the treatment of ventilator-associated pneumonia
The annual congress on inhalation and respiratory drug delivery (April 20-21, 2021) will present the results of preclinical trials of an inhalation phage preparation for the treatment of ventilator-associated pneumonia.
30.03.2021
The National Institutes of Health (USA) supports research in the field of phage therapy
NIAID (USA) is implementing a comprehensive program to support research into the use of bacteriophages in the treatment and prevention of antibiotic-resistant infections. In the first phase, NIAID awarded 12 grants totaling $2.5 million to American universities and companies.
18.03.2021
Bacteriophages in the treatment of infected diabetic foot: state of affairs
Jessica Sacher, editor-in-chief of the weekly online publication Capsid & Tail, spoke about the challenges of treating infected foot ulcers in patients with diabetes, as well as the possibilities of phage therapy for this pathology.
10.03.2021
Antibiotic resistance in Ukraine according to the results of the AURA study (Part 2)
The medical journal "Health of Ukraine. Surgery, Orthopedics, Traumatology, Intensive Care" No. 5, 2020, published the first part of an article by Professor I. Bereznyakov, dedicated to the state of antibiotic resistance in Ukraine based on the results of the AURA study.
26.02.2021
A catalog of bacteriophages inhabiting the human intestine has been compiled
Scientists have compiled the most comprehensive catalog to date of bacteriophages inhabiting the human gut. They have identified over 142,000 bacterial virus genomes and identified some of their characteristics.
16.02.2021
Pharmacokinetics of an oral phage preparation against Klebsiella pneumoniae
Pharmacokinetic studies of a phage preparation for oral use in the treatment of inflammatory bowel diseases/primary sclerosing cholangitis have been successfully completed in phase 1a clinical trials under the FDA IND protocol.
07.02.2021
A phage drug against acne is being prepared for phase II trials
Phase II clinical trials of a topical bacteriophage-based skin care product for acne-prone skin are planned to begin this year.
01.02.2021
Antibiotic resistance in Ukraine according to the results of the AURA study (Part 1)
The medical journal "Health of Ukraine. Surgery, Orthopedics, Traumatology, Intensive Care" No. 4, 2020, published the first part of an article by Professor I. Bereznyakov, dedicated to the state of antibiotic resistance in Ukraine based on the results of the AURA study.