The weekly online publication Capsid & Tail suggests considering bacteriophages as the basis for creating "vaccine cocktails" against COVID-19, providing long-term protection against various strains of the SARS-CoV-2 coronavirus.
The annual congress on inhalation and respiratory drug delivery (April 20-21, 2021) will present the results of preclinical trials of an inhalation phage preparation for the treatment of ventilator-associated pneumonia.
NIAID (USA) is implementing a comprehensive program to support research into the use of bacteriophages in the treatment and prevention of antibiotic-resistant infections. In the first phase, NIAID awarded 12 grants totaling $2.5 million to American universities and companies.
Jessica Sacher, editor-in-chief of the weekly online publication Capsid & Tail, spoke about the challenges of treating infected foot ulcers in patients with diabetes, as well as the possibilities of phage therapy for this pathology.
The medical journal "Health of Ukraine. Surgery, Orthopedics, Traumatology, Intensive Care" No. 5, 2020, published the first part of an article by Professor I. Bereznyakov, dedicated to the state of antibiotic resistance in Ukraine based on the results of the AURA study.
Scientists have compiled the most comprehensive catalog to date of bacteriophages inhabiting the human gut. They have identified over 142,000 bacterial virus genomes and identified some of their characteristics.
Pharmacokinetic studies of a phage preparation for oral use in the treatment of inflammatory bowel diseases/primary sclerosing cholangitis have been successfully completed in phase 1a clinical trials under the FDA IND protocol.
Phase II clinical trials of a topical bacteriophage-based skin care product for acne-prone skin are planned to begin this year.
The medical journal "Health of Ukraine. Surgery, Orthopedics, Traumatology, Intensive Care" No. 4, 2020, published the first part of an article by Professor I. Bereznyakov, dedicated to the state of antibiotic resistance in Ukraine based on the results of the AURA study.
Scientists have for the first time manually synthesized bacteriophages with shortened genomes that lyse various strains of Pseudomonas aeruginosa . This experiment could be the first step toward creating new antibacterial agents.
Antibiotic-resistant Acinetobacter baumannii bacteria became antibiotic-sensitive after exposure to bacteriophages. In an attempt to evade the bacteriophages, the bacteria mutated in a way that made them vulnerable to antibiotics.
Bacteriophages are currently being explored as a promising means of microbial control in agriculture and fisheries. A special issue of the journal PHAGE: Therapy, Applications, and Research is devoted to this topic.
A new method for treating colon and rectal cancer has been proposed based on both natural and GM bacteriophages specific to the pathogenic bacterium Fusobacterium nucleatum .
After a kidney transplant, Maria developed an Escherichia coli infection with multiple antibiotic resistance. A two-week course of intravenous phage therapy completely eliminated the pathogen.
According to data from 24 clinical studies, the proportion of patients with COVID-19 and bacterial infections was 6.9%. Of these, 71.9% received antibiotics.
The US Food and Drug Administration (FDA) has approved the use of bacteriophages in critically ill COVID-19 patients with secondary bacterial infections that are multiply resistant to antibiotics.
Dear colleagues, We invite you to the 20th International Scientific and Practical Conference "Modern Trends in Wound Surgery" on November 26-27, 2020. One of the topics of discussion will be the potential use of bacteriophages in the treatment of chronic ulcers.
Dear colleagues, we invite you to the 5th Scientific Congress with international participation, "Current Issues in Pediatric Gastroenterology," on November 26-27, 2020. Participants will receive a certificate worth 25 BPR points.
