The use of antibiotics has become the norm in modern animal husbandry, as these drugs not only help prevent bacterial infections in animals but also contribute to their weight gain. The result is the spread of antibiotic resistance.
A combination of bacteriophage and antibiotic treatment has resulted in significant improvement in the condition of a sea turtle that had suffered from a chronic bacterial shell infection resistant to most antimicrobial agents for four years.
Now, data collection on antibiotic resistance can be carried out by medical institutions providing specialized or highly specialized medical care, as well as independent bacteriological laboratories.
A monovalent vaccine based on phage-like particles carrying SARS-CoV-2 virus antigens ensures the synthesis of neutralizing antibodies, long-lasting and effective protection against infection
A model has been created that allows simulating the microenvironment of the human body and modeling the interaction of bacteriophages and bacteria within it.
Antibiotic therapy for chronic bacterial prostatitis is often ineffective. A paper has been published describing a clinical case of treating this disease with bacteriophages.
Bacteriophages cannot always completely destroy bacteria that have formed a biofilm. Combination therapy with bacteriophages and other antimicrobial agents is more effective.
The University of Sydney has proposed a new model for preclinical research into optimal combinations of phages and antimicrobial agents for the treatment of bacterial infections, including antibiotic-resistant ones.
Successful phage therapy for antibiotic-resistant bacterial infection helped prevent limb amputation in a child.
"Training" phages to coevolve with bacteria allows them to bypass bacterial resistance mechanisms.
The 24th International Bacteriophage Conference, the oldest and most renowned gathering of scientists and enthusiasts of bacterial virus research, was held at The Evergreen College in Olympia, Washington, USA, on August 2-5, 2021.
Uncontrolled proliferation of C. difficile is observed predominantly in patients with significant disturbances in the intestinal microbiota due to long-term antibiotic therapy.
After analyzing human stool samples, scientists identified 54,118 types of viruses, most of which turned out to be bacterial viruses – bacteriophages.
Phase I/II clinical trials are designed to evaluate the efficacy and safety of personalized phage preparations in patients with urinary tract infections (UTIs) caused by multidrug-resistant bacteria.
Scientists have created a phage cocktail of five mycobacteriophages with broad specificity against M. tuberculosis strains. The properties of the bacteriophages in the cocktail were further optimized using genetic and genetic engineering approaches.
None of the 43 antibiotics currently in various stages of testing address the problem of multidrug resistance in dangerous pathogenic bacteria.
Bacteriophages as a treatment for infections caused by multidrug-resistant bacteria hold great potential for patients who have suffered spinal cord injuries. Doctors from the University Hospital of Zurich discuss this in an article in the journal Spinal Cord.
A new PCR test has been developed for the early diagnosis of Lyme disease. The test detects a gene belonging not to the bacteria that causes the disease, but to a specific bacteriophage. If the bacteriophage is found, then the bacteria is present!
