Children who received at least one course of antibiotics during the first two years of life have an increased risk of developing allergies, celiac disease, obesity, and attention deficit hyperactivity disorder.
Due to their unique properties, namely the ability to target bacteria with high specificity, bacteriophage endolysins can be incorporated into innovative skin care products.
October 22 is World Bacteriophage Day, which kicks off World Bacteriophage Week, which runs until October 28. Congratulations to everyone interested and involved!
Springer has released the textbook "Bacteriophages: Biology, Technology, Therapy" (English). All sections of the book are now freely available.
Patient enrollment is open for phase I/IIa clinical trials to evaluate the efficacy and safety of topical application of a drug based on bacteriophage Endolysins for the treatment of atopic dermatitis.
The new treatment method does not involve introducing any phages into the human body, but it is designed to “awaken” lysogenic phages, which are usually present in any bacteria in the form of prophages.
A comparison of the history of antibiotic therapy in individuals with and without inflammatory bowel disease showed that the risk of developing this chronic pathology increases significantly due to systemic use of antibiotics.
In the PHAGE-2 clinical trial, adding bacteriophages to a probiotic containing bifidobacteria improved gut health and gut microbiota in healthy adult volunteers.
Three projects funded by the Cystic Fibrosis Foundation are focused on phage therapy for antibiotic-resistant chronic infections in patients with cystic fibrosis.
Indian scientists have isolated a lytic bacteriophage specific to the bacterium Klebsiella pneumoniae – the causative agent of severe infections of the respiratory tract, urinary tract, and wounds – and demonstrated its therapeutic efficacy in an animal model of pneumonia.
Mastitis (inflammation of the mammary gland) in dairy cows is a problem that leads to significant losses for farms and is also a cause of excessive use of antibiotics and, consequently, the spread of antibiotic resistance.
The SOAR study focuses on determining the susceptibility of key community-acquired respiratory tract infection pathogens Streptococcus pneumoniae and Haemophilus influenzae to antibacterial drugs.
Australian scientists have published the results of a study on the effect of a phage cocktail against Staphylococcus aureus in mice with a diabetic foot model infected with multidrug-resistant S. aureus.
The cultivation of aquatic organisms such as fish, mollusks, and crustaceans requires constant bacterial monitoring. As the use of antibiotics becomes increasingly problematic, the use of bacteriophages in aquaculture is being considered.
An approach called phage biocontrol involves the use of lytic bacteriophages to treat food products and surfaces that come into contact with them to kill pathogenic bacteria.
Methane, a greenhouse gas, is a byproduct of microorganisms living in the digestive tract of ruminants. Bacteriophages are currently the most promising method for suppressing the activity of methanogenic microorganisms.
The journal Phage published a review examining the potential use of bacteriophages in the fight against the SARS-CoV-2 coronavirus, primarily to reduce mortality in patients with acute respiratory syndrome.
Scanning electron microscopy reveals the "everyday life" of bacteriophages: phage A25 attacks Streptococcus pyogenes bacteria
