Antibiotic-resistant Acinetobacter baumannii bacteria became antibiotic-sensitive after exposure to bacteriophages. In an attempt to evade the bacteriophages, the bacteria mutated in a way that made them vulnerable to antibiotics.
Bacteriophages are currently being explored as a promising means of microbial control in agriculture and fisheries. A special issue of the journal PHAGE: Therapy, Applications, and Research is devoted to this topic.
A new method for treating colon and rectal cancer has been proposed based on both natural and GM bacteriophages specific to the pathogenic bacterium Fusobacterium nucleatum .
After a kidney transplant, Maria developed an Escherichia coli infection with multiple antibiotic resistance. A two-week course of intravenous phage therapy completely eliminated the pathogen.
According to data from 24 clinical studies, the proportion of patients with COVID-19 and bacterial infections was 6.9%. Of these, 71.9% received antibiotics.
The US Food and Drug Administration (FDA) has approved the use of bacteriophages in critically ill COVID-19 patients with secondary bacterial infections that are multiply resistant to antibiotics.
Dear colleagues, We invite you to the 20th International Scientific and Practical Conference "Modern Trends in Wound Surgery" on November 26-27, 2020. One of the topics of discussion will be the potential use of bacteriophages in the treatment of chronic ulcers.
Dear colleagues, we invite you to the 5th Scientific Congress with international participation, "Current Issues in Pediatric Gastroenterology," on November 26-27, 2020. Participants will receive a certificate worth 25 BPR points.
Children who received at least one course of antibiotics during the first two years of life have an increased risk of developing allergies, celiac disease, obesity, and attention deficit hyperactivity disorder.
Due to their unique properties, namely the ability to target bacteria with high specificity, bacteriophage endolysins can be incorporated into innovative skin care products.
October 22 is World Bacteriophage Day, which kicks off World Bacteriophage Week, which runs until October 28. Congratulations to everyone interested and involved!
Springer has released the textbook "Bacteriophages: Biology, Technology, Therapy" (English). All sections of the book are now freely available.
Patient enrollment is open for phase I/IIa clinical trials to evaluate the efficacy and safety of topical application of a drug based on bacteriophage Endolysins for the treatment of atopic dermatitis.
The new treatment method does not involve introducing any phages into the human body, but it is designed to “awaken” lysogenic phages, which are usually present in any bacteria in the form of prophages.
A comparison of the history of antibiotic therapy in individuals with and without inflammatory bowel disease showed that the risk of developing this chronic pathology increases significantly due to systemic use of antibiotics.
In the PHAGE-2 clinical trial, adding bacteriophages to a probiotic containing bifidobacteria improved gut health and gut microbiota in healthy adult volunteers.
Three projects funded by the Cystic Fibrosis Foundation are focused on phage therapy for antibiotic-resistant chronic infections in patients with cystic fibrosis.
Indian scientists have isolated a lytic bacteriophage specific to the bacterium Klebsiella pneumoniae – the causative agent of severe infections of the respiratory tract, urinary tract, and wounds – and demonstrated its therapeutic efficacy in an animal model of pneumonia.
