The British broadcaster BBC included phage therapy for antibiotic-resistant infections in its list of the most important medical achievements of humanity in 2019.
Danish scientists are working on developing a phage preparation to prevent diarrhea caused by enterotoxigenic E. coli in pigs.
Finnish scientists have shown in animal studies that bacteriophages on the mucous membrane protect against the penetration of pathogenic bacteria.
Bacteriophages are a promising method of combating phytopathogenic bacteria, the mechanism of action of which has three components
A startup developing bacteriophage-based methods for combating cholera outbreaks has won the TropMed19 tropical medicine competition in the United States.
There are arguments in favor of the fact that the development of alcoholic liver disease is associated, among other things, with certain microorganisms, in the fight against which specific bacteriophages can be used
Young children who received two or more courses of antibiotics for ARIs within a year had an increased risk of not responding to subsequent courses of antibiotics.
Swiss researchers have genetically modified phages so that they recognize and attack a wider range of bacterial strains than their wild ancestors.
More and more data is emerging on the interaction of bacteriophages not only with their host bacteria but also with the human immune system. Studying the mechanisms of such interactions could form the basis for the development of new anti-inflammatory and immunomodulatory agents.
Every year, doctors increasingly encounter H. pylori resistance to antibiotics included in the recommended treatment regimens for this common infection. Clarithromycin, in particular, is rapidly losing its effectiveness.
The human intestine is normally home to not only bacteria (microbiome) but also viruses (virome), primarily bacteriophages. The virome is represented by many types of bacteriophages, and its composition varies from person to person.
Scientists have proposed a new strategy for rapidly producing phage preparations to combat various strains of pathogenic bacteria. To do this, they induce a mutation in the phage gene encoding a protein that binds to the target bacterium.
Antibiotic-resistant mycobacterial infections, particularly tuberculosis, pose a serious challenge to modern medicine. Bacteriophages are being considered as a possible alternative to antibiotics in the treatment of tuberculosis.
In August 2019, the 23rd Evergreen International Phage Meeting was held at Evergreen State College in Olympia, Washington, USA. The conference is held every two years and is one of the world's most important scientific events dedicated to bacteriophages.
The value of the study is not only that the effectiveness of phage prophylaxis against salmonellosis in poultry farming has been proven, but also that it will help phages gain the trust of private farmers.
A cocktail of several bacteriophages successfully combated a strain of E. coli pathogenic to humans without harming the intestinal microbiota in mice experiments.
Phage biocontrol is a "green" technology that helps to specifically destroy pathogenic microorganisms in food products without affecting their organoleptic properties.
Scientists from McMaster University (Canada) have packed a huge number of bacteriophages so tightly that they form a stable gel-like structure.
