In 2019, two clinical trials of phage drugs will begin in the United States. The first experimental drug is intended for the treatment of Crohn's disease, and the second is for the treatment of patients with VAD devices infected with resistant staph.
American Pharm Exec Magazine surveyed leading investment experts about the most important areas of drug development in 2019. Among the top 10 trends, they named the development of phage therapy as a treatment for antibiotic-resistant infections.
The Third European Summit of the Microbiome Movement - Drug Development Europe will be held in Paris on January 28-30, 2019. The summit will focus on the development, production and commercialization of "microbiome" drugs, including those based on bacteriophages.
Infectious diseases and their treatment with antibiotics may increase the risk of developing certain mental disorders in childhood and adolescence.
Treatment of salmonella infection with bacteriophages is highly specific and, unlike antibiotic therapy, does not disturb the balance of intestinal microbiota.
A bacteriophage has been described that begins to destroy bacteria in response to certain signals exchanged between them.
We present to your attention an online resource that presents, in a convenient, visual, interactive form, up-to-date information on the spread of antibiotic resistance in different countries around the world, as well as trends in the use of antibiotics in medicine and agriculture.
A systematic review found that phage therapy is effective and safe for treating infections caused by ESCAPE bacteria, pathogens that are most often resistant to antibiotics and are responsible for the majority of hospital-acquired infections.
More than 33,000 people died in the EU and the European Economic Area (EU/EEA) due to antibiotic-resistant bacterial infections in 2015 alone.
In October 2018, The Lancet published the final report on the international PhagoBurn project, which aimed to evaluate the clinical potential of bacteriophages in the treatment of burn wounds infected with Escherichia coli and Pseudomonas aeruginosa.
A liposome can become a "Trojan horse" that will help bacteriophages enter cells and destroy intracellular bacterial pathogens.
In October 2018, Credence Research (USA) published the report “Bacteriophage Market - Growth, Future, Competitive Analysis, 2018-2026,” which analyzed the key trends in the global bacteriophage market.
IDWeek, the largest annual American forum dedicated to infectious diseases, took place in San Francisco from October 3-7, 2018. Phage therapy as a treatment for antibiotic-resistant infections was the topic of one of the IDWeek plenary sessions.
The 2018 Nobel Prize in Chemistry was awarded for the development of methods for the directed evolution of peptides and proteins, in particular phage display technology. What is its essence? How do phages aid in the development of modern medicines?
At the Pasteur Institute (France), the influence of host immunity on the effectiveness of phage therapy of acute pneumonia caused by a multidrug-resistant strain of Pseudomonas aeruginosa was studied in mice.
Twenty-one patients in seven hospitals with severe, life-threatening bacterial infections that were unresponsive to antibiotics were given phage preparations against Staphylococcus aureus or Pseudomonas aeruginosa as part of an open-access program.
Seasonal and daily dynamics of the population of the pathogenic bacterium Burkholderia pseudomallei in the natural environment largely depends on bacteriophages
Every year, about a million people die from bacterial infections resistant to most antibiotics. Which "superbugs" are the most common and dangerous?
