When a child is sick, parents seek not only effective but also safe treatment. This is especially true for bacterial infections, which are often treated with antibiotics. In such cases, the question arises: are bacteriophages safe for children? After all, a child's body is sensitive and not yet fully developed. Any intervention must be as gentle as possible, yet still effective.
In recent years, phage-based medications have increasingly been prescribed in pediatrics. This is due to their selectivity, their ability to destroy only pathogenic bacteria without affecting the body's normal microflora.
First of all, it should be emphasized that bacteriophages are viruses that infect and destroy only bacteria. They do not affect human cells, do not penetrate the body's DNA, and do not cause allergic reactions in the vast majority of cases. This is why phage therapy is considered safe even for newborns.
Many pediatricians in Ukraine and abroad are already using phages to treat infections in children. For example, for intestinal infections, tonsillitis, sinusitis, bronchitis, pyelonephritis, and post-surgical complications.
Bacteriophages are selective, killing only the bacteria they target. This means they don't "burn out" everything, as is often the case with antibiotics.
Another advantage is the lack of toxicity. Bacteriophage-based medications do not burden a child's liver or kidneys. They can be administered not only orally, but also rectally, topically, and in some cases, even by inhalation or as drops.
Despite the high safety of phages for children, some nuances should be taken into account.
First and foremost, it's important to select the correct bacteriophage for the type of bacteria. Therapy will only be effective if the specific pathogen causing the infection is known. Therefore, bacteriological analysis is sometimes performed before treatment.
In pediatric practice, so-called polyvalent bacteriophages—those that act on several types of bacteria simultaneously—are often used. This allows treatment to begin before test results are available.
Another important aspect is the form of administration.
For newborns, it is convenient to use rectal suppositories or enemas with a phage solution.
For older children, oral forms are available in the form of syrups, solutions or tablets.
If we are talking about a throat infection, it is advisable to use gargles or aerosol forms of phages.
In cases where a child has chronic respiratory infections, a doctor may prescribe inhalations of bacteriophages through a nebulizer. This allows the medication to penetrate deep into the bronchi, where the pathogen often hides.
It should be noted that bacteriophages for children have virtually no side effects.
Very rarely, minor reactions such as abdominal discomfort or short-term bloating may occur, which resolve without intervention.
One of the advantages of phage therapy is its compatibility with other drugs.
Bacteriophages can be used together with probiotics, immunostimulants, and even antibiotics (although it is advisable to use them only when necessary).
This combination is sometimes necessary in complex cases, such as infections caused by resistant bacteria.
It is important to note that phage therapy in children does not suppress the immune system.
On the contrary, some studies suggest that it may help build a more stable immune system by maintaining the natural balance of microflora.
There are cases when bacteriophages are prescribed to children even for prophylactic purposes—after surgery or during an epidemic rise in infectious diseases.